Why Does IVF Fail ?

Why Does IVF Fail

Why Does IVF Fail ?

What is IVF treatment?
How does IVF work?

IVF treatment is a complicated medical procedure which involved risks so unpredictable things can happen even with the best efforts. Unfortunately, many couples will not get success in first cycle of IVF and have to consider a second cycle no doubt unsuccessful IVF cycle is emotionally and financially devastating. Why does IVF fail sometimes?  Following are the main reasons,

Issues with the Follicles
Egg Abnormalities
Female Age
Abnormal Sperm
IVF Lab Factors
Embryo Selection Methods
Issues with the Uterus and Uterine Lining
Embryo Implantation Failure
Embryo Transfer Process

Issues with the Follicles

Follicles are small sacks, filled with fluid, in which eggs are matured. These follicles are located in the ovaries. Fertility drugs are used in order to promote the growth of follicles and then to trigger ovulation and the release of viable eggs. If the follicles are too small or not viable, this can lead to failure of the process.

Egg Abnormalities

The egg is the most important factor considered for the cause of IVF failure. An IVF treatment can be failed if egg quality is poor.If the eggs that are produced for the process may not be viable for treatment, the possibility of success gets low.

Female Age

High doses of drugs used to stimulate the ovaries of older women undergoing fertility treatment may be causing chromosomal abnormalities in their eggs. Age has a great impact on the egg. After age 30 egg quantity and quality begin to decline and the rate accelerates after age 35, so that by age 40 only about 10% of a woman’s eggs are normal. 

Abnormal Sperm

Sperm quality issues are another potential cause of an IVF cycle failure. This can generally be dealt with through sperm washing techniques and careful selection of healthiest sperm present.

Why Does IVF Fail
                                                                            Why Does IVF Fail

IVF Lab Factors

Once treatment plan has been set by a doctor, it becomes the responsibility of the IVF lab to execute the plan according. The scientists who supervise embryo growth are called embryologists.In rare instances, errors on the part of the fertility center or a fertility specialist can lead to a failure of an in vitro fertilization (IVF) treatment. Modern technology and advanced techniques have helped reduced the already low possibility of fertility doctor error.

Embryo Selection 

In an IVF cycle, embryos are observed for 3 to 5 days as they grow, before they are transferred into the uterus. On the third day, good-quality embryos should reach 6- to 8-cell stage, and have a more or less regular shape. Embryos that don’t reach this stage within the first few days of development cannot be used for embryo transfer. Timing is key when it comes to transferring embryos to the uterus. If the embryos are implanted too soon (i.e., before proper cellular division) or at some other poorly timed moment, the chances of successful pregnancy are reduced.
Embryos with abnormal numbers of chromosomes almost always result from an issue with the egg.

Issues with the Uterus and Uterine Lining

The lining of the uterus must grow to a certain thickness (at least 7 mm) for implantation to occur at a high rate. It’s important that fertility specialists consider the possibility of uterus or uterine lining issues before the transfer phase is even initiated. If the lining is not perfect, the transfer should be deferred. So there are many answers of this question that Why does IVF fail ?

Embryo Implantation Failure

There are times when the embryo simply fails to attach to the uterine lining, or instead implants on another part of the woman’s reproductive system, such as the fallopian tubes.

Embryo Transfer

Embryos are generally transferred to the woman’s uterus at the 2-8 cell stage and is considered the simplest and final step of IVF process.There are minimal risks associated with the embryo transfer procedure and sometimes mistakes are made. For instance, it’s possible for an embryo to become damaged or lost during the transfer phase of the treatment or implanting the embryos in the wrong place such as the Fallopian tubes.

IVF again?

If the first IVF treatment goes unproductive, second IVF procedure can be considered. Unexpected things can happen in this complex procedure so couples should go if the first attempt fails because this is not the end of the world.

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